Department of Medical Laboratory

In line with the mission of the University which is to develop the human mind to be creative, innovative, research oriented, competent in areas of specialization, knowledgeable in entrepreneurship and dedicated to service, the Medical Laboratory Science Department offers courses leading to the award of Bachelor of Medical Laboratory Science (BMLS) Honours degree.
Medical Laboratory Science is a promising dynamic profession that is designed to provide a broad basis of fundamental scientific knowledge and its application such that the graduands are well prepared to meet with changing needs of modern scientific knowledge considering their pivotal role in Health care delivery system. The training exposes students to application of medical laboratory science in key areas such as clinical diagnostic services, food and beverages, pharmaceutical industries, Breweries, utility departments e.g. Water Corporation, academic and research institutions.
DEPARTMENT OF MEDICAL LABORATORY SCIENCE
BACHELOR OF MEDICAL LABORATORY SCIENCE
(BMLS) PROGRAMME
ACADEMIC STAFF OF THE DEPARTMENT
S/N NAME QUALIFICATIONS RANK
Dr. F.O. Akinbo B.Sc., AIMLS, M.Sc., Ph.D. Associate Professor /
Ag. HOD
Prof. I. N. Ibeh Ph.D., AIMLS,
M.Sc. MNAAS, FIIAS Professor
Prof. (Rev.) Dr. F.E. Oronsaye AIMLS, M.Sc., D.D, Ph.D. Professor
Prof. H. B. Osadolor AMLSCN, FMLSCN, M.Sc., Ph.D., FASCP Professor
Dr. M.A. Emokpae FMLSCN, M.Sc., Ph.D. Associate Professor
Dr. M.A. Okungbowa AMLSCN, FMLSCN, M.Sc., Ph.D. Associate Professor
Dr. (Mrs) E.O. Osime AIMLSC, FIMLSC, M.Sc., Ph.D. Associate Professor
Dr. (Mrs) H.O. Ogefere B.Sc., AIMLS, M.Sc., FMLSCN, Ph.D. Associate Professor
Dr. G.O. Igharo B.MLS, PGD (Edu), M. Tech, AMLSCN, Cert. Forensic Toxicology, M.Sc., Ph.D. Senior Lecturer
Mr. O.F. Amegor M.Sc., PGD, AIMLS. Lecturer I
Dr. B.I.G. Adejumo MMLS, FIMLT AIBMS, Ph.D. Lecturer I
Dr. B.E. Odigie B.MLS, M.Sc., Cert. in Immunohistochemistry & Frozen Section Techniques AMLSCN, ACSMLS, Ph.D. Lecturer I
Dr. (Mrs.) Zainab Omoruyi B.Sc., AIMLS, M.Sc., Ph.D. Lecturer I
Mr. A.I. Aruomaren AMLSCN, B.MLS, M.Sc. Lecturer I
Mrs. I.M. Moses-Otutu AMLSCN, B.MLS, M.Sc. Lecturer II
Mrs. P.A. Obazelu AMLSCN, B.MLS, M.Sc. Lecturer II
Mrs. J. O. Osunbor AMLSCN, B.MLS, M.Sc. Lecturer II
Mrs. B. O. Onuyoh AMLSCN, B.MLS, M.Sc. Lecturer II
LABORATORY SCIENTIST/TECHNOLOGIST
S/N NAME QUALIFICATIONS RANK
Mrs. L.A. Emokpae AIMLS, M.Sc Chief Med. Lab. Scientist (Medical Microbiology)
Mr. O. Williams AIMLS Principal Med. Lab. Scientist (Medical Microbiology)
Mrs. A. N. Olise AIMLS, M.Sc. MLS Principal Med. Lab. Scientist (Medical Microbiology)
Mr. F. U. Uzamere AIMLS Principal Med. Lab. Scientist (Haematology/Transfusion Science)
Mrs. E. Otamere AIMLS Principal Med. Lab. Scientist (Clinical Chemistry)
Mr. N.S. Owie B.MLS Senior Med. Lab. Scientist (Haematology/Transfusion Science)
Mrs. F. Newton-Esebelahie B.MLS Senior Med. Lab. Scientist (Medical Microbiology)
Mrs. S. Oronsaye B.MLS Senior Med. Lab. Scientist (Medical Microbiology)
Mrs. H. Efeziri B.MLS Senior Med. Lab. Scientist (Medical Microbiology)
Mr. N. Dimowo B.MLS Senior Med. Lab. Scientist (Haematology/Transfusion Science)
Mrs. I. Omusi B.MLS, M.Sc Senior Med. Lab. Scientist (Medical Microbiology)
Mr. M. I. Elaiho B.MLS Med. Lab. Scientist (Haematology/ Transfusion Science)
Mr. F. O. Osula B.MLS Med. Lab. Scientist (Histopathology)
Mr. B. E. Odozi B.MLS, M.Sc Med. Lab. Scientist (Haematology/ Transfusion Science)
Miss E. O. Ehigiator B.MLS Med. Lab. Scientist (Medical Microbiology)
Mr. O.A. Igiebor B.MLS Med. Lab. Scientist (Clinical Chemistry)
Miss E.J. Onaghinor B.MLS Med. Lab. Scientist (Haematology/ Transfusion Science)
Mrs. B.E. Ogeyemhe B.MLS, M.Sc., Cert. in Immunohistochemistry & frozen Section Techniques Med. Lab. Scientist (Histopathology)
Mrs. I. Erhabor B.MLS Med. Lab. Scientist (Medical Microbiology)
Mr. S. Ogieriakhi C.MLA Senior Med. Lab. Assistant
ADMINISTRATIVE/EXECUTIVE STAFF
S/N NAME QUALIFICATIONS RANK
Mrs. I. Ugiagbe B.Sc., M.Sc. Administrative Officer
Mrs. I.O. Sotubo B.Sc. Administrative Assistant
Mrs. E. A. Isaiah Diploma in Pub. Admin., B.Sc. Principal Executive Officer I
Mrs. E. Evbuomwan 50 W.P.M Senior Typist II
Mrs. G. Ijekhuemen S.S.C.E Chief Clerical Officer
Mrs. M. Ikekele WAEC, NTI Senior Clerical Officer
INTRODUCTION
In line with the mission of the University which is to develop the human mind to be creative, innovative, research oriented, competent in areas of specialization, knowledgeable in entrepreneurship and dedicated to service, the Medical Laboratory Science Department offers courses leading to the award of Bachelor of Medical Laboratory Science (BMLS) Honours degree.
Medical Laboratory Science is a promising dynamic profession that is designed to provide a broad basis of fundamental scientific knowledge and its application such that the graduands are well prepared to meet with changing needs of modern scientific knowledge considering their pivotal role in Health care delivery system. The training exposes students to application of medical laboratory science in key areas such as clinical diagnostic services, food and beverages, pharmaceutical industries, Breweries, utility departments e.g. Water Corporation, academic and research institutions.
The training exposes students to basic services, basic medical sciences and to core areas like Clinical Chemistry, Haematology/ Blood Transfusion Science, Medical Microbiology/Parasitology, Histopathology, Immunology/Immunochemistry as well as instrumentation and laboratory management.
Mode of admission is by UTME (5–year programme) and by Direct Entry (4-year programme). Students accepted for the BMLS programme are expected to register with the Medical Laboratory Science Council of Nigeria (MLSCN) and be indexed as student members soon after admission into the programme. On successful completion of the BMLS programme, induction into the profession and mandatory one year internship preceding participation in the NYSC programme, graduates are registered as Associate members (AMLSCN) with the professional body, Medical Laboratory Science Council of Nigeria, subject to meeting its other requirements.
PHILOSOPHY
The Bachelor of Medical laboratory Science degree is designed to:
Highlight the central role of the laboratory investigation of components of biological fluids, blood, urine, cerebrospinal fluid, secretions, excretions, tissues or organs, play in the diagnosis, management and prognosis of disease state.
Have sufficient management ability to play a leadership role in training and the practice of Medical Laboratory Science.
Enable students acquire the expertise to produce biological and diagnostic reagents as well as fabricate new equipment or repair or even modify existing ones and refine old techniques or introduce new diagnostic procedures.
AIMS/OBJECTIVES
To organize and offer courses and such related studies to undergraduate students as may be prescribed by the Senate of the University and Medical Laboratory Science Council of Nigeria leading to the award of the degree of Bachelor of Medical Laboratory Science (BMLS).
To train and develop undergraduate students to fill the manpower needs of the country in Medical Laboratory Science.
To produce Medical Laboratory Scientists who satisfy International standards and who can undertake further training towards specialization.
To train up research scientists who are able to carry out researche in the various disciplines of Medical Laboratory Science.
ADMISSION REQUIREMENTS
Admission through UTME:
Candidates must satisfy the minimum University requirements for admission and are therefore to obtain credits in five subjects of English Language, Mathematics, Biology, Physics and Chemistry in SSCE or its equivalent in not more than two sittings.
In addition to the above, the candidate must have an acceptable score in the Unified Tertiary Matriculation Examination (UTME) conducted by JAMB.
Admission by Direct Entry:
Candidates holding three GCE A/L in Biology, Chemistry and Physics plus O/L Credits in five subjects of English Language, Mathematics, Biology, Physics and Chemistry.
Candidate who transfers from other faculties of the University with relevant prerequisites.
B.Sc. degree in relevant science disciplines like Zoology, Microbiology, Anatomy, Physiology, Biochemistry, etc; as approved by the senate.
HND in relevant fields as approved by the senate.
No transfer is allowed. Please see MLSCN Accreditation Report.
COURSE DURATION
The Bachelor of Medical Laboratory Science degree programme shall run for five (5) years for UTME candidates and four (4) years for direct entry candidates.
REGISTRATION OF COURSES
At the beginning of the session, the students must register for all the courses specified for the respective session.
NOTE:
The 100 level students will spend their first year in the Faculties of Life and Physical Sciences. The students will subsequently move along until 300 level when they will be given special attention in the department.
EVALUATION OF STUDENTS
Each MLS Course taught in the BMLS Programme at the University may be evaluated for grading with the use of one or several of the following criteria:
Written examinations which include problem solving:-
a. Essay: Six (6) questions to attempt four (4).
b. Multiple choice question (MCQ) 40 questions (5 parts) to attempt all.
Laboratory presentations or demonstrations to the class of exercises/techniques.
Laboratory Reports.
Case studies/Laboratory logbook.
Continuous assessment tests.
No students shall be allowed into the examination venue if he/she has not fulfilled the mandatory posting.
CONTINUOUS ASSESSMENT
Continuous Assessment (CA) during the Semester shall form part of the end of course grade. Its overall contribution shall be 30% of each course examination.
END OF THE YEAR OVERALL ASSESSMENT
The pass mark for 100, 200 and 300 level students in the department shall be 45% while 400 and 500 level students pass mark shall be 50%.
A student shall be deemed to have passed his/her examinations if he/she passes in all the compulsory and required courses he/she registered for during the academic year. Any 500 level student who at the end of final year examinations accumulate less than the prescribed total minimum credits or does not pass in all the required courses but who has accumulated the required minimum credits to remain in the department will be required to register or take the course(s) in the following session and to sit for the appropriate examinations.
ATTENDANCE POLICIES
Attendance is compulsory and absences from class and/or laboratories will affect student’s final grade. Missed laboratory work and/or examinations must be completed.
Since sample procurement is difficult, laboratory absences are particularly difficult to make up 75% attendance is a prerequisite to sit exams. Absence from laboratory postings is tantamount to carry over of posting. Students are therefore advised not to miss any laboratory session.
Protracted illness (three consecutive days or more) should be reported to the head of Department promptly.
Students shall continue their laboratory posting during holidays and this shall serve as their industrial attachment.
Final year students are to take compulsory call-duty in their respective Discipline. They are to be attached to Medical Laboratory Scientist on- call-duty. This shall be graded part of the 75% attendance laboratory posting.
GRADUATION REQUIREMENTS
Deferred entry requirement: e.g. credit pass in English at SSCE or GCE O/L.
THERE ARE NO DEFERRED ENTRY REQUIREMENTS
Minimum number of credit hours: 222
Minimum number of years of the Course: 5 years (UTME) and 4 years (DE)
Minimum CGPA 1.50 – 2.39
CLASSIFICATION OF DEGREE:
A Grade Point Average (GPA) shall be calculated for each level of course. The students’ final grade form the sum of the weighted Grade Point Average for each level of the courses is as follows:
5 year Degree Programme 4 year Degree Programme
100 level 10% 200 level 10%
200 level 15% 300 level 20%
300 level 20% 400 level 30%
400 level 25% 500 level 40%
500 level 30%
COMPUTATION OF GRADE POINT AVERAGE (GPA)
To compute a grade point average (GPA) for a candidate, his total aggregate point for the session will be divided by the total credit load for the session.
N.B.
Core courses are courses, which all students must take and pass before they can graduate.
Mandatory courses are courses, which students must take but do not have to pass before they can graduate.
The class of degree is determined by the final Cumulative Grade Point Average (CGPA) as follows:
Class of Degree CGPA
First Class Honours 4.50 – 5.00
Second Class Honours (Upper Division) 3.50 – 4.49
Second Class Honours (Lower Division) 2.40 – 3.49
Third Class Honours 1.50 – 2.39
PERFORMANCE GRADE IN EACH COURSE
PERCENTAGE SCORES LETTER GRADE GRADE POINT
70 – 100 A 5
60 – 69 B 4
50 – 59 C 3
45 – 49 D 2
0 – 44 F 0
PROFESSIONAL EXAMINATION
Students are required to satisfy examiners in professional examinations to be moderated by external examiners in the various Medical Laboratory Science disciplines which will be observed by a representative of Medical Laboratory Science Council of Nigeria. The examinations shall be in two parts viz:
First Professional Examinations to be held last Semester of the forth year shall consist of two parts;
Papers I and II – consists of practical examination in Medical Microbiology, Parasitology, Haematology, Blood Transfusion Science, histopathology, Chemical Pathology.
Candidate will be required to attempt question in Parasitology, and in any 4 of the other core subjects.
Questions shall include steeple chase spot questions-3 hours.
Viva voce (Oral) examination
A pass in this examination is a prerequisite for the 500 level.
Final Professional Examination to be 2nd Semester of final graduating year which shall consist of practical and oral examinations in the specialty discipline of the candidate. There shall be two papers in morning and afternoon sessions.
Pass mark in both examinations is 50% i.e. C grade point
Resit examinations may be conducted not later than 3 months after the main examination.
Eligibility: Only students without any re-sit or carry-over are eligible to sit for professional exams.
EXAMINATION MISCONDUCT
The following sanctions shall apply to cases of examination misconduct as stipulated below.
S/N MISCONDUCT SANCTION
Proven cases of fore-knowledge of Examination Questions (Leakage) Expulsion of all involved.
Coming into Examination Hall with extraneous materials Rustication for a minimum period of 4 Semesters or Expulsion if fore-knowledge of Questions is proven.
Writing on any materials in the Examination Hall, other than the Answer Booklet Letter of warning
Non production of Identity card or authorized letter of identification before and during examination. To leave the Examination Hall immediately
Any form of unauthorized communication between and among students during examination To lose 10 minutes of examination time; if it persists, relocate the student; further persistence cancel the paper.
Impersonation at Examination Expulsion of all involved.
Refusal to fill Examination Misconduct Form Rustication for (2) Semesters plus penalty for the original offence.
Attempt to destroy or actually destroying materials of proof of cheating Rustication for (2) Semesters plus penalty for the original offence.
Refusal to obey invigilator’s instructions such as:
Writing after the Examination Has been Stopped.
Noncompliance with the invigilator’s sitting arrangement
Letter of Warning
To leave the hall and carry-over the course
Refusal to submit Answer scripts (used and unused) at the close of examination Rustication for a minimum period of (2) Semesters.
Smuggling of Question papers and Answer Booklets out of the Hall for help and returning with Answer Scripts Expulsion
Failure to write matriculation numbers on Answer Booklet or to sign Attendance Sheet Letter of Warning
Writing of candidate’s names on Answer Booklets Letter of Warning
Leaving Examination Hall without permission To carry-over the course and Letter of Warning
Failure to draw a line through each blank space at the end of each answer Letter of Warning
Unruly behavior in the Examination Hall such as smoking, drinking of liquor, noise etc Verbal warning by Invigilator. If unruly behavior persists, to leave the Hall and carry over the course
Proven cases of physical assault on Invigilator/Attendant Expulsion
Failure to appear before Misconduct Panel Guilty as charged. Indefinite suspension pending appearance before the Panel.
Any students with three (3) letters of warnings Rustication for a minimum period of one (1) Session.
Any other cases of Examination malpractice not specified Punishment as appropriate.
WITHDRAWAL FROM DEPARTMENT
Students who accumulate 11-21 credits in the session are either to seek inter faculty/department transfer or remain in the department on probation.
Students who fail to accumulate less than 11 credits at the end of the second semester examination will be asked to withdraw from the department.
Any student who has previously transferred from another faculty/department or gone on probation and still fails to obtain 22 credits after the sessional examination shall withdraw from the department.
The Senate (if satisfactory reasons are given) may grant a student temporary withdrawal from the school. The student could be allowed to register and take the examination in the required courses at the next available opportunity provided, he does not exceed the maximum number of years required for the degree.
COURSE CODE SYSTEM
Course code contains an abbreviated letter code of three (3) letters and three (3) digits.
MLS – is a prefix that indicates the department
The first digit represents the level of study.
The second digit denotes the semester for 100 – 400 Levels while for 500 Level the second digit denotes specialty area.
The third digit denotes the topic/stress area.
DRESS CODE
MALE: A good pair of trousers (not jeans) with neat shirt, a matching tie and a pair of shoes.
FEMALE: Corporate gown with sleeve or skirt (not jeans) below the knee with sleeved shirt/blouse and a pair of shoes.
Student professional Lapel pin should be worn always on their dresses/shirt
Wearing of Laboratory coat is compulsory for all clinical laboratory postings and practical classes.
COURSE CODE, COURSE TITLE AND CREDIT LOAD
FIRST YEAR (100L) COURSES
FIRST SEMESTER
COURSE CODE COURSE TITLE CREDIT LOAD LTP
AEB111 Introductory Zoology 4 303
BMS111 Elementary Mathematics 2 200
CHM111 General Chemistry I 3 203
CHM113 Organic Chemistry I 3 203
GST111 Use of English I 2 200
GST112 Philosophy & Logic 2 200
PBB111 Introduction to Plant Biology I 3 203
PHY111 Mechanics, Thermal Physics & Properties of Matter 3 203
PHY113 Vibrations, Waves & Optics 3 203
TOTAL: 25
SECOND SEMESTER
COURSE CODE COURSE TITLE CREDIT LOAD LTP
AEB122 Functional Zoology 4 303
CHM122 General Chemistry II 3 203
CHM124 Organic Chemistry II 3 203
GST121 Peace Studies and Conflicts Resolution 2 200
GST122 Nigerian People & Culture 2 200
GST123 History & Philosophy of Science and Technology 2 200
PBB122 Introduction to Plant Biology II 3 203
PHY109 Practical Physics 2 222
PHY124 Electromagnetism and Modern Physics 4 303
TOTAL: 25
All Courses are core at this Level. Total Credit Load for the Session…….50
SECOND YEAR (200L) COURSES
FIRST SEMESTER
COURSE CODE COURSE TITLE CREDIT LOAD LTP
MLS211 Introduction to Medical Laboratory Science I 2 200
ANT210 General Anatomy and Gross Anatomy of the Upper Limbs 2 203
ANT211 Gross Anatomy of Thorax 2 203
ANT212 Basic Histology & Cytology 2 203
ANT213 General Embryology 2 200
MBC210 Introductory Biochemistry 2 200
PHS211 Introductory and General Physiology 2 200
PHS212 Blood and Body fluid Physiology 2 203
PHS213 Cardiovascular System 2 200
PHS214 Respiratory Physiology 2 200
CSC110 Introduction to Computing 3 203
TOTAL: 23
SECOND SEMESTER
COURSE CODE COURSE TITLE CREDIT LOAD LTP
MLS222 Introduction to Medical Laboratory Science II 2 201
ANT220 Gross Anatomy of the Abdomen, Pelvis and Perineum 2 200
ANT222 Systemic Histology 1 3 203
ANT223 Systemic Embryology 1 3 203
MBC220 Carbohydrate & Lipid Metabolism 3 203
MBC223 Amino acid & Protein Metabolism 3 203
MBC225 Protein Chemistry & Enzymology 3 203
PHS221 Renal Physiology 2 200
PHS222 Gastrointestinal Physiology 2 200
PHS223 Endocrinology & Reproduction 3 203
PHS224 Temperature Regulation 1 100
TOTAL: 27
TOTAL CREDIT LOAD FOR THE SESSION………………50
THIRD YEAR (300L) COURSES
FIRST SEMESTER
COURSE CODE COURSE TITLE CREDIT LOAD LTP
MLS310 Laboratory Posting I (SIWES) 3 016
MLS311 Medical Laboratory Science Ethics 2 200
MLS312 Introduction to Medical Laboratory Science III 3 200
MLS313 Medical Physics 3 201
MLS314 Basic Clinical Chemistry 3 203
MLS315 Basic Immunology 2 200
MBC312 Intermediary Metabolism 2 210
CED 300 Introduction to Theory & Practice of Entrepreneurship 2 210
TOTAL 20
SECOND SEMESTER
COURSE CODE COURSE TITLE CREDIT LOAD LTP
MLS320 Laboratory Posting II (SIWES) 3 016
MLS321 Introductory Microbiology 2 203
MLS322 Laboratory Instrumentation & Techniques 3 302
MLS323 Fundamental Blood Transfusion Science 3 203
MLS324 Basic Haematology 3 203
MLS325 General Pathology (Basic Histopathology) 3 203
MLS326 Laboratory Management & Organization 2 200
PCO320 Introductory Pharmacology 2 200
TOTAL 21
TOTAL CREDIT LOAD FOR THE SESSION……………..41
Industrial attachment in accredited hospital or medical/research laboratory for a period of three months. Supervision and training in the hospital laboratory shall be conducted by consulted medical laboratory scientists with current practicing license issued by Medial Laboratory Science Council of Nigeria.
FOURTH YEAR (400L) COURSES
FIRST SEMESTER
COURSE CODE COURSE TITLE CREDIT
LOAD LTP
MLS410 Laboratory Posting III (SIWES) 3 016
MLS411 Medical Parasitology & Entomology 3 203
MLS412 Basic Medical Bacteriology & Mycology 3 203
MLS413 Introduction to Haemoglobin, Haemoglobinopathy & Myeloproliferation 3 203
MLS414 Introduction to Blood Group Systems & Compatibility Tests 3 203
MLS415 Analytical Chemistry 3 203
MLS416 Introduction to Cytology 2 202
MLS417 Nucleic Acid Biochemistry & Basic Concepts of Molecular Biology 2 200
TOTAL 22
SECOND SEMESTER
COURSE CODE COURSE TITLE CREDIT
LOAD LTP
MLS420 Laboratory Posting IV (SIWES) 3 016
MLS421 Biostatistics 2 200
MLS422 Virology 3 203
MLS423 Introduction to Histopathology Techniques and Museum 3 203
MLS424 Biomedical Engineering 2 200
MLS425 Biotechnology & Bioinformatics 2 203
MLS426 Counseling skills 2 200
MLS427 Immunology/Immunochemistry 3 203
TOTAL 20
TOTAL CREDIT LOAD FOR THE SESSION………………42
FIRST PROFESSIONAL EXAMINATION – PRACTICAL AND VIVA
FIFTH YEAR (500L) COURSES
CLINICAL CHEMISTRY (SPECIALTY)
FIRST SEMESTER
COURSE CODE COURSE TITLE CREDIT
LOAD LTP
MLS510 Laboratory Posting V (SIWES) 3 016
MLS511 Seminar 2 020
MLS512 Research Methodology 3 300
MLS531 Carbohydrate, protein and Lipid Metabolism 3 203
MLS532 Renal, Liver and Neurochemistry 3 203
MLS533 Clinical Enzymology 3 203
MLS534 Nutrition and Clinical Vitaminology 2 202
TOTAL 19
SECOND SEMESTER
COURSE CODE COURSE TITLE CREDIT
LOAD LTP
MLS520 Laboratory Posting VI (SIWES) 3 016
MLS521 Genetics & Molecular Biology 2 200
MLS522 Project 6 008
MLS535 Drug Monitoring, Toxicology & Inborn Error of Metabolism 3 203
MLS536 Clinical & Reproductive Endocrinology 3 203
MLS537 Techniques in Clinical Chemistry 3 203
TOTAL 20
TOTAL CREDIT LOAD FOR THE SESSION………………39
FINAL PROFESSIONAL EXAMINATION – PRACTICAL & VIVA
HAEMATOLOGY & BLOOD TRANSFUSION SCIENCE (SPECIALITY)
FIRST SEMESTER
COURSE CODE COURSE TITLE CREDIT
LOAD LTP
MLS510 Laboratory Posting V (SIWES) 3 016
MLS511 Seminar 2 020
MLS512 Research Methodology 3 300
MLS513 Cytogenetics 2 200
MLS541 Haemopoiesis, Haemoglobin, Haemoglobinopathies & Myeloproliferations 3 203
MLS542 Blood Group Systems & Compatibility Tests 3 203
MLS543 Serology & Blood Transfusion Science 3 203
TOTAL 19
SECOND SEMESTER
COURSE CODE COURSE TITLE CREDIT
LOAD LTP
MLS520 Laboratory Posting VI (SIWES) 3 016
MLS521 Genetics & Molecular Biology 2 200
MLS522 Project 6 008
MLS544 Advanced Haematological Techniques 3 203
MLS545 Advanced Blood Group Serology Techniques 3 203
MLS546 Coagulation and Fibrinolysis Studies 3 203
TOTAL 20
TOTAL CREDIT LOAD FOR THE SESSION………………39
FINAL PROFESSIONAL EXAMINATION – PRACTICAL & VIVA
HISTHOPATHOLOGY (SPECIALITY)
FIRST SEMESTER
COURSE CODE COURSE TITLE CREDIT
LOAD LTP
MLS510 Laboratory Posting V (SIWES) 3 016
MLS511 Seminar 2 020
MLS512 Research Methodology 3 300
MLS513 Cytogenetics 2 200
MLS551 Fundamental Histopathology 3 203
MLS552 Systemic Histopathology 3 203
MLS553 Histochemistry and Histological Techniques 3 203
TOTAL 19
SECOND SEMESTER
COURSE CODE COURSE TITLE CREDIT
LOAD LTP
MLS520 Laboratory Posting VI (SIWES) 3 016
MLS521 Genetics & Molecular Biology 2 200
MLS522 Project 6 008
MLS554 Medical Cytology 2 202
MLS555 Embalment Science and Museum Techniques 2 203
MLS556 Immunochemistry 2 202
MLS557 Stains and Staining Techniques 3 203
TOTAL 20
TOTAL CREDIT LOAD FOR THE SESSION………………39
FINAL PROFESSIONAL EXAMINATION – PRACTICAL & VIVA
MEDICAL MICROBIOLOGY (SPECIALITY)
FIRST SEMESTER
COURSE CODE COURSE TITLE CREDIT
LOAD LTP
MLS510 Laboratory Posting V (SIWES) 3 016
MLS511 Seminar 2 020
MLS512 Research Methodology 3 300
MLS561 Systemic Bacteriology 3 203
MLS562 Advanced Entomology 2 203
MLS563 Public Health Microbiology 3 202
MLS564 Medical Mycology 3 203
TOTAL 19
SECOND SEMESTER
COURSE CODE COURSE TITLE CREDIT
LOAD LTP
MLS520 Laboratory Posting VI (SIWES) 3 016
MLS521 Genetics & Molecular Biology 2 200
MLS522 Project 6 008
MLS565 Medical Virology 3 220
MLS566 Pharmaceutical Microbiology & Microbial Genetics 3 203
MLS567 Laboratory Techniques in Microbiology 3 203
TOTAL 20
TOTAL CREDIT LOAD FOR THE SESSION………………39
FINAL PROFESSIONAL EXAMINATION – PRACTICAL & VIVA
A SUMMARY OF THE CREDIT LOAD FOR THE PROGRAMME
LEVEL CREDIT LOAD TOTAL CREDIT LOAD
100 50
200 50
300 41
400 42
500 Chem. Pathology 39 222
OR
500 Haem/BTS 39 222
OR
500 Histopathology 39 222
OR
500 Med. Microbiology 39 222
DESCRIPTION OF COURSES
100 LEVEL COURSES:
AEB111: INTRODUCTORY ZOOLOGY 3-0-3 (4 Credits)
Man population growth and impact on the biosphere. Faunal biodiversity.
Invertebrate – protozoa, coelenterate, platyhelminthes, annelida, mollusca, arthropoda.
Vertebrata – Cephalochordata, pisces, amphibian, reptilia, aves, mammalia. Mammalian anatomy: anatomy of rattus rattus.
BMS111: ELEMENTARY MATHEMATICS 1 2-0-0 (2 Credits)
Polynomials and their factorization, rational function. Trigonometry definitions and elementary properties of trigonometric function, radian measure, periodicity of identities. Formulas for sum, product and quotient. The chain rule. Differentiation of definite and indefinite algebraic, trigonometric, exponential and logarithmic functions maxims and minima, tangential and normal. Fundamental theory of calculus, simple application to areas and volumes, Methods of integration.
CHM111: GENERAL CHEMISTRY 1 2-0-3 (3 Credits)
Relationship of chemistry to other sciences, Atoms, sub-atomic particles, isotopes, molecules, Avogadro’s number, Mole concept. Dalton’s theory. Modern concepts of atomic theory. Laws of chemical combination. Relative atomic masses.
Introduction to nuclear reactions, Nuclear binding energy, fusion and fission reactions.
States of Matter: Gases, gas laws, general gas equation, liquids and solids.
Introduction to lattice structure. Isomorphism, giant molecules.
Introduction to the periodic table, hydrogen and hydrides, chemistry of groups: 0. I,II elements. Acid-Base properties of oxides.
CHM113: ORGANIC CHEMISTRY I 2-0-3 (3 Credits)
General principles of organic chemistry: Definition, classification, homologous series, functional groups; General procedure for isolation and Purification of organic compounds, Structure of organic compounds, Elemental analysis, percentage composition, empirical and molecular formula, structural formula.
Isomerism: structural and stereoisomerism; Electronic theory in organic chemistry.
Non-polar functional groups: Alkanes, Alkenes, Alkynes, Benzene.
Nomenclature: Common names, IUPAC names; Introduction too petrochemistry, Coal tar chemistry.
GST111: USE OF ENGLISH 1 2-0-0 (2 Credits)
Modes and methods of effective communication in English. Use of literary works to improve communication skills. Development of reading and writing skills. Note taking and summarizing from oral English and written instructions on lexis. Collection for written assignments.
GST112: PHILOSOPHY AND LOGIC 2-0-0 (2 Credits)
Introduction to the main branches of philosophy, symbolic logic. Special symbol in symbolic logic. Conjugation, negation, affirmation, disjunction, equivalence and conditional statements. Law of thought. Method of deduction using rules of inference and biconditional qualification theory.
PBB111: INTRODUCTION TO PLANT BIOLOGY I 2-0-3 (3 Credits)
Morphology and life circle of plant and animals. A general study of plant and animal groups from virus, algae/fungi to chordates. Structural and functional study of plants and animal cells, tissues, organs and systems. Taxonomic, physiological and developmental studies of plant and animals. Reproduction, genetic, hereditary substances, mechanism of nuclear division and stem cell formation. Evolution and natural selection. Biology practicals and demonstrations.
PHY111: MECHANICS, THERMAL PHYSICS AND PROPERTIES OF MATTER
2-0-3 (3 Credits)
Scalars and vectors: Addition and Resolution of Vectors. Rectilinear Motion and Newton’s laws of Motion. Inertial mass and gravitational Mass; Free fall; projectile motion, deflecting forces and circular motion. Newton’s law of Gravitation; Satellites, escape velocity. Gravitational Potential well; special case of circular motion. Laws of thermodynamics and thermal energy, temperature, calorimetry, change of state, critical points. Heat transfer, conduction, convection and radiation. Blackbody radiation. Gas laws. Kinetic theory of gases. Model for matter; surface energy and surface tension, plastic deformation; thermal and electrical properties of metals.
PHY113: VIBRATIONS, WAVES AND OPTICS 2-0-3 (3 Credits)
Periodic motion of an oscillator; velocity and acceleration of a sinusoidal oscillation, equation of motion of a simple harmonic oscillator: damped oscillations, forced oscillations, resonance, and propagation of longitudinal and transverse vibrations.
Wave behaviour; Reflection of waves, stationary waves, propagation of straight and circular pulses, Fibre optics. Diffraction, Refraction, Dispersion, Interference, Coherence, Polarisation.
Wave and Light: Mirrors, Lenses, formation of images, lenses in contact microscope, telescope, chromatic and spherical aberrations and their reduction. Dispersion by prisms; relation between colour and wavelength, spectra.
SECOND SEMESTER
AEB122: FUNCTIONAL ZOOLOGY 3-0-1 (4 Credits)
Embryology–gametogenesis, fertilization and cleavage as demonstrated by Amphioxus, Genetics: the cell and distribution of genetic material, mitosis, meiosis, meiosis inheritance, sex determination and sex linked inheritance. Histology. Cells, tissues, organ formation and main features. Physiology: functioning of mammalian skin, muscles/skeleton, alimentary system/nutritional requirements and deficiencies.
CHM122: GENERAL CHEMISTRY II 2-0-3 (3 Credits)
Acids, Bases and salts. Quantitative and qualitative analysis. Theory of volumetric analysis-operations and methods. Calculations: mole, molarity, molality. Behavior of electrolytes. Water. Colligative properties. Ostwald’s dilution law. Arthenius, Bronsted-Lowry, lewis concepts and applications. Buffers – introduction to reaction rates. Equilibria and equilibrium constants. Solubility products. Common effects. Precipitation reactions, Chemistry of Redox reactions.
CHM124: ORGANIC CHEMISTRY II 2-0-3 (3 Credits)
Polar function group chemistry. Hydroxyl group carbonyl group, carboxylic group Carboxylic acid derivatives and amino acids. Miscellanceous topics – fats and oils, amino acids, proteins, carbohydrates and natural products.
GST121: PEACE STUDIES AND CONFLICTS RESOLUTION 2-0-0 (2 Credits)
GST122: NIGERIAN PEOPLE AND CULTURE 2-0-0 (2 Credits)
History, norms and cultural characteristics of African and the Nigerian society in particular, role of culture in the behaviors of Nigerian. The African society, development, migration, large and small rural movements and its effect on man and disease, the Nigerian rural and urban societies and diseases. Changing patterns of diseases in rural and urban societies. Changing moral values. Cultural nationalism and political evolution of African states. concepts of religion in humanistic functions. Role and concepts of functional education in national development.
GST123: HISTORY & PHILOSOPHY OF SCIENCE AND TECHNOLOGY
2-0-0 (2 Credits)
PBB122: INTRODUCTION TO PLANT BIOLOGY II 2-0-3 (3 Credits)
The general morphology, anatomy, histology and physiology of flowering plants, seed structure, dispersal and germination: development of primary and secondary plant body; water relations; photosynthesis, translocation, and storage organs, respiration.
PHY109: PRACTICAL PHYSICS 2-2-2 (2 Credits)
Students are expected to carry out a minimum of 12 major experiments covering the main aspects of the courses taken in the year.
PHY124: ELECTROMAGNETISM AND MODERN PHYSICS 3-0-3 (4 Credits)
Electromagnetism – electric field: strength, flux and the inverse square law; electrostatic force between two charged particles; flux model for the electric field. Energy stored in an electric field, electrical potential due to dipole.
Steady direct current: Simple circuits, potential difference, resistance, power, electromotive force, Kirchoff’s laws, Potential divider, slide wire potentiometer, bridge circuits, combining resistances.
Capacitors; Capacitance, combination of dielectrics, energy store charging/discharging.
Electromagnetic effects: Electromagnetic forces, electric motors, moving coil galvanometer, ammeter, voltmeter, electromagnetic induction, dynamo.
Alternating currents: Simple AC circuit, transformers, motors and alternating currents.
Magnetic field: The field at the center of a current carrying flat coil, of a current carrying solenoid, outside a long solenoid; flux model and magnetic fields.
200 LEVEL COURSES:
MLS211: INTRODUCTION TO MEDICAL LABORTORY SCIENCE I 2-0-0
(2 credits)
General introduction to medical laboratory science subjects namely, Clinical Chemistry, Haematology and Blood Transfusion Science. Medical Microbiology, Histopathology and Immunology, Specimen collection, reception and registration. Storage and disposal, Specimen bottle. Safety precaution in pathology laboratories against chemical, biological, electrical materials and radiation hazards. Techniques and principles of chemical sterilization and physical methods. Glassware cleaning care and maintenance, Breeding of laboratory animals.
ANT210: GENERAL ANATOMY AND GROSS ANATOMY OF THE UPPER LIMBS 2-0-3 (2 credits)
The general descriptive terms as used in the study of the human body would be introduced. The techniques used to study the human body would also be introduced. The normal anatomical position and directional movement of body parts would be introduced.
The gross anatomy of the upper limbs: pectoral region, Axilla, Brachial plexus, scapular region, brachium, carpal tunnel, Hand, Nerve injuries, oseteo-logy and joint of the upper limb, the vascular anastomosis and lymphatic drainage of the breast and upper limb would be studied.
ANT211: GENERAL GROSS ANATOMY OF THORAX 2-0-3 (2 credits)
Description of the thorax: The sternum and ribs, thoracic vertebrae, Heart and great vessels, thoracic duct, dissection of the entire thoracic region, Azygos system of vein, intercostal spaces, Mediastinum, lungs bronchiopulmonary tree and segments, thoracic diaphragm, Aorta and respiratory movement. Dissected specimens will be demonstrated to the students.
ANT212: GENERAL BASIC HISTOLOGY AND CYTOLOGY 2-0-3 (2 Credits)
Description: Structure and the function of the cell, general histology and basic tissues of the body. Preparation of tissues for microscopy is a practical oriented course that is studied along side with the theoretically based lecture.
ANT213: GENERAL EMBRYOLOGY 2-0-0 (2 Credits)
General consideration of the male and female reproductive organs. Gametogenesis, fertilization, implantation, cleavage, the morula, the blastocyst formation of the primitive streak, the Bilaminar and trilaminar germ disc. Development of tissues and organ systems of the embryo, the chorionic and amniotic cavities. Foetal membranes, placental formation and functions. The molecular regulation in differentiation of tissues and organs and in the establishment and patterning of the body axis. Birth defects, chromosomal and genetic factors. Twins and twin defects, general characteristics of the embryonic environment and foetal periods.
MBC210: INTRODUCTORY BIOCHEMISTRY 2-0-0 (2 Credits)
Short history and Definition of Biochemistry. Importance of Biochemistry to medicine and other scientific disciplines. The living cell. Organization and Molecular architecture. Types of cells and their characteristics. Structure and organization of Biological membranes. Biomolecules and the origin of life. Chemistry of Biomolecules. Carbohydrates Classification, structure, distribution and functional role of named examples. Chemical properties and reactions. Essential fatty acids, Eicosanoids, fat-soluble vitamins – Structure and functions. Peptide bonds and hierarchy of protein structure Nucleic acids. RNA and DNA. Structure/function of enzymes. Zymogens. Active site and specificity of enzymes. Inhibition and Activation of enzymes. Factors affecting enzyme catalyses reaction. Allosteric enzymes. Isoenzymes. The Concepts of Avitaminoses, Hypovitaaminoses and Antivitamins. Vitamins and their Co-enzyme function. Biomedical importance of vitamins.
PHS211: Introductory and General physiology 2-0-0 (2 Credits)
Cell physiology, Physiochemical principles, Body fluids and Blood transport: Control systems. Excitable and contractile Cells. Introduction to ANS.
PHS212: BLOOD AND BODY FLUID PHYSIOLOGY 2-0-3 (2 Credits)
Introduction and definition of body fluids and body fluid compartments. Regulation of body fluid volumes. Physiological variation of body fluid volumes. Techniques for quantifying various body fluid volumes.
Blood: Functions of blood and classifications of blood cells. Erythropoiesis. Haematological indices. Haemoglobin genotype and Blood groups. Immunology and cell defence
PHS213: CARDIOVASCULAR SYSTEM 2-0-0 (2 Credits)
Definition and functions of the cardiovascular system, Cardiac muscle, Cardiac myoelectrophysiology, cardiac cycle, Circulation of blood: cardiac output and regulation. Blood pressure. Haemodynamics and microcirculation. Pulmonary, Cerebral, Coronary, Splanchnic and muscle circulation, Shock and cardiovascular changes in exercise.
PHS214: RESPIRATORY PHYSIOLOGY 2-0-0 (2 Credits)
Definition and functions of the respiratory system, Physiologic anatomy of the respiratory system. Respiratory dynamics and work. Pulmonary ventilation: Lung volumes and capacities, Spirometry. Mechanism and mechanics of breathing, Lung surfactant, pulmonary circulation. Gas exchange and Gas transport. Oxygen Haemoglobin dissociation curve. Hypoxia and Dyspnoea. Respiratory changes in exercise and barometric changes. Control of breathing.
CSC110: INTRODUCTION TO COMPUTING 2-0-3 (3 credits)
The course introduces the history of Computers, functional components of a computer, characteristics of a computer, problem solving flowcharts and algorithm. It also includes basic computer programming statement, Symbolic names: arrays subscripts expression and control statements and introduction to visual basic programming computer applications.
SECOND SEMESTER
MLS222: INTRODUCTION TO MEDICAL LABORATORY SCIENCES II 2-0-1
(2 Credits)
Microcopy and micrometry-use and care of microscopes. Refrigeration and freeze-dries-principles, uses, care and maintenance. Handling of laboratory animals. Laboratory location and floor plan. Laboratory organization and management. Simple analytical techniques in chemical pathology. Presentation of volumetric analysis. Urinalysis, principles of tissues preservation; fixation, processing and staining. Handling of surgical autopsy specimens. Removal of formal in pigments, basic, tools of the microbiologist-wire loop cotton wool, pipettes, swab and their uses, preparation of films and basic staining techniques: Gram’s stain, Ziehl Nelson’s stain. Hematological stain principle and components. Blood film preparation and staining, pipettes, chambers care and uses. Haemoglobin, PCV estimation, WBC counting.
ANT220: GROSS ANATOMY OF THE ABDOMEN, PELVIS AND PERINEUM
2-0-3 (2 Credits)
Abdomen: subdivision of the abdominal region and their applied anatomy, Anterior Abdominal wall, inguinal region, posterior abdominal wall, stomach, spleen, liver, gall bladder, pancreas, small and large intestine, celiac trunk, biliary apparatus, intra and supra colic compartment and recesses, appendix renal and suprarenal gland, dissection of the entire abdominal region for proper understanding of the entire region.
Pelvis & perineum: pelvic cavity wall and diaphragm. Urinary bladder, uterus, ovary, etc). Perineum, boundaries and subdivisions. Perineal pouches, external and internal genitalia, ischiorectal fossas. General dissection of the pelvis and perineal region.
ANT222: SYSTEMIC HISTOLOGY I 2-0-3 (3 Credits)
Systemic histology of cardiovascular system, gastrointestinal tract and musculoskeletal system.
ANT223: SYSTEMIC EMBRYOLOGY I 2-0-3 (3 Credits)
The diaphragm, the cardiovascular, respiratory and gastro intestines systems. Development of the adrenal gland, the liver, the pancreas and the spleen. The urogenital, Musculo-skeletal and integumenary system. The limbs, the molecular regulation and associated developmental anomalies of the systems.
MBC220: CARBOHYDRATE AND LIPID METABOLISM 2-0-3 (3 Credits)
Structural inter-relationships of sugars. Stereochemistry of sugars. Hexoses, Pentoses, Disaccharides, Starch, Glycogen, and Polysaccharides. Methods of identifying sugars. Carbohydrate metabolism. Digestion and absorption. Glycolysis. TCA Cycle and Pentose Phosphate pathway. Control of Glycolysis. TCA Cycle and Pentose Phosphate pathway. Glyoxylate Pathway. Gluconeogenesis. Glyoxylate Pathway. Gluconeogenesis. Glycogenolysis and Glycogenesis. Mitochondrail electron transport chain and Oxidative Phosphorylation. Energy generation and storage in Biological systems.
Disorders of Carbohydrate Metabolism. The pyruvate and α–Ketoglutarate complexes and their regulation. Metabolism of lipids. Digestion and absorption. Role of Lipoproteins in lipid transport. Metabolism of lipoprotein in health and disease. Triacylglycerol oxidation and oxidation of fatty acids. Storage and mobilization of energy stores in adipocytes. Ketone bodies and Ketosis.
Interrelationship of fatty acid and carbohydrate biosynthesis/oxidation. Biological importance of Eicosanoids. glycolipids and sphingolipids. The Chemistry and metabolism of Steroids and Steroid hormones.
MBC223: AMINO ACID AND PROTEIN METABOLISM 2-0-3 (3 Credits)
Structure of amino acids. Peptide bonds. Metabolism and transport of amino acids and proteins. Digestion and absorption. Gammaglutamyl cycle. Detailed treatment of mechanism of deamination, transamination. Glutamate Dehydrogenase, Glutamate and Glutamine synthesis. The biochemical and clinical importance of these enzymes. Fate of Carbon skeleton. Urea cycle. The concepts of nitrogen balance. Nitrogen turnover in cells. Degradation of amino acids. Ketogenic and glucogenic amino acids. Aromatic acid degradation and inborn errors of metabolism, metabolism of uric acid. Integration and Compartmentation in intermediary metabolism. Metabolism of one carbon compounds.
MBC225: PROTEIN CHEMISTRY AND ENZYMOLOGY 2-0-3 (3 Credits)
A review of the Structural Characteristic of proteins. Determination of N and C terminal amino acid. Amino acid sequence and sulphide bridges. Determination of Protein Structure by X-ray Crystallography. Biological functions of proteins. The oxygen transporting proteins (haemoglobin and myoglobin), connective tissue protein. Collagen and Elastin. Structure/function relationships.
Enzymes. Isolation and Purification from animals, plants and microorganisms. Zymogens and Isoenzymes. Characteristics of enzymes. Kinectics of enzyme catalysed reaction. Allosterism. Importance of enzymology in Medicine. Coenzymes and relationships to vitamins.
PHS221: RENAL PHYSIOLOGY 2-0-0 (2 Credits)
Definition and functions of the kidney. Physiologic anatomy of the kidney. Glomerular filtration. Tubular functions. Urine formation:- Dilute and concentrated urine. Counter current mechanism, Plasma clearance, renal autoregulation, ECF regulation, Acid-Base balance, Renin-Angiotensin system.
PHS222: GASTROINTESTINAL PHYSIOLOGY 2-0-3 (2 Credits)
Definition and functions, Physiologic anatomy and Innervations of the GIT, Mastication, Deglutition, Salivary gland, Digestion and food absorption, Movement and Stomach emptying, Movements of the GIT, Vomiting and defecation, GIT secretions and juices, Liver and General metabolism (BMR).
PHS223: ENDOCRINOLOGY AND REPRODUCTION 2-0-0 (3 Credits)
Definition and functions, Definition of Hormones, Methods of Measurement, Types and mechanism of Actions, Regulation, Physiologic anatomy, Hypothalamo-Hypothalamic releasing factors, Hypothalamic Nuclei, Hypothalamo-hypophyseal system, Pituitary gland, Tropic Hormones, GIT and other local hormones.
Structure and functions of male and female reproductive organs, Androgens, Spermatogenesis and fertility. Infertility in male. Monogenesis, Sexual cycle and hormonal regulations. Fertilization, Pregnancy and Parturition, Fertility and infertility in female. Family planning.
PHS224: TEMPERATURE REGULATION 1-0-0 (1 Credit)
Body temperature and the environment, Mechanisms of heat Exchange, peripheral, thermoreceptors, central thermoreceptors, hyperthermia, and hypothermia, Fever, heat Exhaustion and Heat stroke.
300 LEVEL COURSES:
MLS310: LABORATORY POSTING I (SIWES) 0-1-6 (3 Credits)
Posting of students to all sections of routine medical laboratories for on the job training under the supervision of qualified medical laboratory scientists for 2 days weekly for the entire semester. Scored log books are kept by each student per posting.
MLS311: MEDICAL LABORATORY SCIENCE ETHICS 2-0-0 (3 credits)
History and philosophy of ethics in the practice of Medical Laboratory Science. Relationship between religion and socio—cultural values on medical ethics. Ethical issues involved in private practice. Relationship between the Medical laboratory scientist and other members of the health team. Intra professional auditing, Medical aboratory Sciences ethic and consultancy services. Elements of informed consent in research. Relationship between proper dressing, personal comportment and patient care-the psychologist’s view: Medical Laboratory Science ethics as it affects paternity disputes, infertility studies, and sexually transmitted disease etc. real case presentation medico—legal aspects of medical Laboratory practice
MLS312: INTRODUCTION TO MEDICAL LABORATORY SCIENCE III 2-0-0 (3 Credits)
Introduction to, parasitism, and other animal associations, adaptation to parasitic way of life. How parasites invade their host. The ineffective agents of parasites. Basic knowledge of structure, classification and life cycle of parasites of medical importance, vectors and intermediate hosts of parasites. Introduction to anthropods of medical importance. Biology of the mosquito in relation to the transmission of malaria, filiariasis and viral infections.
MLS313: MEDICAL PHYSICS 2-0-3 (3 Credits)
Kinematical and mathematical problems—circulation of pulse, blood pressure and volume changes. The heart and blood surface tension effect. Temperature and heat flow/electricity, electrocardiograms, general radiation linear energy transfer and radiation measurement, radiation damage-detection and safety, X-ray generation and application radioisotopes production, use and disposal.
MLS314: BASIC CLINICAL CHEMISTRY 2-0-3 (3 Credits)
Traditional and S. 1 units in clinical chemistry; Reference values: Gastric function test; Agents for Gastric stimulation. Ward procedures and laboratory investigation of Gastric secretion: Intestinal function tests; Digestion and absorption; cause of Malabsorption. Laboratory investigation of malabsorption. Renal functions of the kidney; measurement of Renal plasma flow, Glomerular filtration rate. Creatinine clearance, insulin clearance, concentration and dilution tests; urinary, acidification tests, urine specific gravity/Osmolarity. Dye Excretion test.Water and Electrolyte status. Blood buffers. Transport of blood gases; assessment of acid/base status. Lipids; definition and types of lipids; formation of free fatty acids, Ketone bodies and lactate; measurement of plasma lipids and lipoprotein. Plasma proteins and physiology functions; factors affecting synthesis and catabolism. Methods for the determining of total protein in serum. Carbohydrate metabolism; blood glucose homeostasis, Hyperglycemia diabetes mellitus-its cause and investigation: Hypoglycemia—types causes and investigation.
MLS315: BASIC IMMUNOLOGY 2-0-0 (2 Credits)
The Historical background of Immunology. Classification of Immunity Innate Immunity. Development and structure of cells in the Immune system. Cellular interaction in the expression and regulation of immunity acquired.
MBC312: INTERMEDIARY METABOLISM 2-1-0 (2 Credits)
Integration of Metabolism. The provision of metabolic fuels. Metabolic fuels in the fed and starving states. Metabolic interrelationships between adipose tissue, liver, extra hepatic tissues and muscle. The role of hormones in intermediary metabolism. Regulation of metabolism in adipose tissue.
CED300: INTRODUCTION TO THEORY AND PRACTICE OF ENTREPRENEURSHIP
2-0-0 (2 credits)
You as an Entrepreneur, Getting started. Selecting the legal forms of business. Discovering Business Opportunities. The legal framework for the Entrepreneur. Government policies and Entrepreneurial activities, Ethical Issues in business, financing a new venture. Sources marketing your product and services Employing people, Establishing and maintaining Accounting Records. Budgeting for Control.
SECOND SEMESTER
MLS320: LABORATORY POSTING II (SIWES) 0-1-6 (3 credits)
Posting of students to all section of routing Medical laboratories for on the job training under the supervision of qualified medical laboratory scientist for 2 days per week scored logbook records per bench are kept for each student per posting.
MLS321: INTRODUCTORY MICROBIOLOGY 2-0-3 (2 Credits)
History, Morphology, growth and nutrition. Classification and identification of bacteria. Bacterial genetics, Bacteriophages, viruses, infection and resistance to infection. Sterilization and disinfection. Antimicrobial agents. Introduction to parasites and fungi.
MLS322: LABORATORY INSTRUMENTATION & TECHNIQUES 3-0-2 (3 Credits)
Instrument aspects of qualitative and quantitative analysis – theory and practice of some common analytical techniques; colorimetry, spectroflourimetry flame – photometry, conductometry, polarography etc. Osmometry, nephelometry, Turbidemetry, PH measurement by ion specific electrodes—separation techniques including Electrophoresis; paper, cellulose acetate, Agar gel starch and polyacrylamide gel; Isoelectric focusing, Isotophoresis, Chromatograhy, Ion exchange, Gel filtration, molecular sieves; dialysis filtration, solvent Extraction, centrifugation – Ultracentifiguration, Immunoeletrophoretic techniques, radio immunoassay, competitive protein binding, Isotope dilution techniques; Enzyme Immuno assay, receptor Assay, automation, Micro and Ultra Micro Analysis. Practical based on the above topics.
MLS323: FUNDAMENTAL BLOOD TRANSFUSION SCIENCE 2-0-3 (3 Credits)
ABO and Rhesus Blood Groups, Inheritance, distribution and Genetic Theory. Blood Grouping Techniques –principles, Disadvantages and Advantages. Preparation of Antisera, Antiserum titration avidity, potency and specificity. Plant lectins—preparation and standardization of antisera from lectins e.g Dolochos biflorus. Anticoagulants used in BGS; ACD, CPD-CPA-A etc in modes of action and side effects. Blood bottles (MRC) and plastic Bags-Advantages and disadvantages. Donor screening—using CUSO4 method –other methods of screening. Preparation of blood products—cryoprecipitate, platelet rich plasma, packed cells fresh frozen plasma, fibrinogen etc. storage of blood and blood products- various methods, advantages and disadvantages. Blood banking –organization structures, facilities and records. Blood group specific substance – synthesis, identification method (s) and application. Quality control of physical and chemical reagents. Practical/Tutorials. ABO and Rhesus grouping method Antiserum Titration DCT and ICT antibody screening.
MLS324: BASIC HAEMATOLOGY 2-0-3 (3 Credits)
Origin, development and function of blood cells. Synthesis and breakdown of haeomoglobin. Methods of Haemoglobin estimation. Methods of cell counting. Absolute values. Introduction to Homeostasis. Principles and mode of action of common anticoagulants. Principle and components of Hematological stains. Simple tests used in blood coagulation. Blood films –normal and abnormal practical classes.
MLS325: GENERAL PATHOLOGY (BASIC HISTOPATHOLOGY) 2-0-3 (3 Credits)
Introduction to Histopathology, fixation autolysis bacterial decomposition. Effects of fixation, common fixing agents and their uses. Secondary fixation, post –fixation and post –chroming and post mordating. Fixation, pigments Decalcification. Dehydration, clearing and infiltration/embedding. Frozen and celloidin sections. Embedding media. Basic histology of organs. Principles and application of exfoliative Cytology. Collection and fixation of specimens for Cytological examination. Museum technique- colour restoration. Mounting in museum jars. Tissues and cellular injury inflammation. Healing and repairs. Gross post- mortem slide examination to illustrate normal and abnormal features appearance of diseased organs in routine and common tumours.
MLS326: LABORATORY MANAGEMENT & ORGANIZATION 2-0-0 (2 Credits)
Laboratory Management, planning a medical laboratory including the provision for the reception of patients selection and storage of chemicals, materials and apparatus. Detailed knowledge of the principles, use and maintenance of common laboratory apparatus and equipment. Ventilation, air conditioning and dust control in the laboratory. Equipment used in special workbench e.g cutting—up benches media-pouring, etc sterilization of air. Laboratory hazards and safety measures to be taken in the use of radioactive and dangerous materials. Emergency treatment for accidents. Laboratory Records Maintenance of records: reception, recording storage, filling and indexing of specimens and result. Organization and operation of a system of quality control. Supply Chain Management: Introduction to commodity supplies, SOP Manual for facilities and staff in SCM, Cataloqing and Indexing of Laboratory supplies, Introduction to LMIS, Max-Min, Inventory control system, Adjust Max-Min level. Inventory,storage and distribution of health commodities, Assessing health logistics, system selection,quantification of Medical laboratory and Health commodities, Supply, Planning and Shipment. Introduction to Medical Laboratory commodities procurement, monitory and supervision. Methods of recording experiments.
PCO320: INTRODUCTORY PHARMACOLOGY 2-0-3 (2 Credits)
History of Pharmacology and its development. Introduction to pharmacokinetics; drug absorption and bioavailability. Drug metabolism, pharmacogenetics. Effects of disease on drug kinetics. Drug in pregnancy and the extreme age. Pharmacodynamics; dose-response relationships, LD50 ED50 and TD50. Therapeutic index; introduction of new drugs, clinical trials; adverse drug reactions and adverse reaction surveillance.
400 LEVEL COURSES:
MLS410: LABORATORY POSTING III (SWIES) 0-1-6 (3 Credits)
Posting of students to all sections of routine Medical Laboratories for on the job training under the supervision of qualified Medical Laboratory Scientists, for 2 days per week in the entire semester. Scored logbook records per bench are kept for each student per posting.
MLS411: MEDICAL PARASITOLOGY AND ENTOMOLOGY 2-0-3 (3 credits)
Introduction to the parasites. Classification of protozoa, (the amoebas, the ciliates, the flagellates, Nematodes. (Ascaris, Strongyloidies, Trichuris, Guinea worms, Trichinella Enterobius, etc.). Life cycle and pathogenicity of cestodes. (The tapeworms, Larval forms of Cestodes). Life cycle and pathogenicity of the Trematodes (The Schistosome, fasciola paragonimus, etc.). methods of demonstration of parasite in blood, faces, vagina,urine urethra, pus from lung and liver, skin snips, etc Mechanisms of their disease production; Epidemiology and control of parasitic diseases. Arthropods of medical importance—the crustaceans Arachnida Hexapoda, Myiasis etc-their biology, life cycles and control. Life history as disease vectors various disease of medical importance transmissible by insects. Biology of mosquito in relation to transmission of malarial, filariasis and viral infections etc.
MLS412: BASIC MEDICAL BACTERIOLOGY AND MYCOLOGY 2-0-3 (3 Credits)
Methods for the demonstration of bacterial form and structure. Design and preparation of culture media. Sterilization and other methods of bacterial control. Aseptic procedures and methods for pure culture isolation, procedures for receiving, handling and processing of clinical specimens. Antibiotic assay, sensitivity test and chemotherapy. Plate reading. Principle and techniques of anaerobic bacteriology. Methods of total and viable counts. Stock culture preservation, quality control of culture and media. Record-keeping in Bacteriology laboratory. Staining techniques for spores, capsules and negative staining procedure, wet preparation, motility tests. Introductory mycology.
MLS413: INTRODUCTION TO HAEMOGLOBIN, HAEMOGLOBINOPATHY &
MYELOPROLIFERATIONS 2-0-3 (3 Credits)
Iron metabolism, folate and Vit B 12 metabolism, Nomenclature, classification and investigation of common haemoglo-binopathies, hemolytic anemia’s; myeloproferative disorder; homeostatsis and disorder of homeostasis; investigation of bleeding disorders. Bone marrow. Practical classes.
MLS414: INTRODUCTION TO BLOOD GROUP SYSTEMS & COMPATIBILITY TESTS 2-0-3 (3 credits)
Blood groups –other blood groups e.g MNS, Duffy, Kell, Kidd etc. grouping techniques and antibody screening, clinical significance, serostatus. Antenatal serology – screening and Titration (quantitation) compatibility procedures-different methods, advantage and disadvantages, Blood Transfusion reactions.-causes and types; investigation. Risks attendant in blood transfusion- Diseases, anaphylactic, hemolytic and allergic reactions. Screening of Donor blood for diseases. Compatibility procedures- advantages and disadvantages. Practical based on the above topics.
MLS415: ANALYTICAL CHEMISTRY 2-0-3 (3 credits)
Principles of analytical techniques in clinical chemistry-devising new techniques, biological trials and tests for acceptability. Solid/dry phase chemistry, dipstick technology, thin film technology immobilized enzymes – analytical techniques for qualitative and quantitative determination of enzymes, hormones, proteins, lipid, trace elements, non-protein nitrogen, volumetric analysis -partition, adsorption, gel filtration, ion exchange and gas liquid chromatography. Electrochemical analysis- principles of potentiometric analysis. Fractionation of proteins-fractional precipitation (salting out), chromatographic and electrophoretic procedures. Protein precipitants-mode of action and choice in analytical procedures.
MLS416: INTRODUCTION TO CYTOLOGY 2-0-2 (2 Credits)
Collection, selection and preparation of cytology specimens (Cervical smear, Vaginal smear, Bronchial aspirates, ascitic fluids and other fluids). Cytology staining techniques, normal, atypical and malignant cells. Cornification index. Maturation index, progesterone/androgen effects.
MLS417: NUCLEIC ACID BIOCHEMISTRY AND BASIC CONCEPTS OF MOLECULAR BIOLOGY 2-0-0 (2 Credits)
Nomenclature of bases, nucleosides and nucleotides. Nucleic acids. Hydrolysis of nucleic acids. Analysis of nucleotide sequence in nucleic acids and its application in diagnosis of diseases. Nucleic acid protein complexes. Genetic role,structure and replication of DNA. Introduction to polymerase chain reaction and its application in laboratory diagnosis.
SECOND SEMESTER
MLS420: LABORATORY POSTING IV (SIWES) 0-1-6 (3 Credits)
2 days weekly for the entire semester. Scored log books are kept by each student per posting.
MLS421: BIOSTATISTICS 2-0-0 (2 Credits)
Aims, characteristics and application of biostatistics in biomedical sciences- samples, population variables, frequently distribution, vital and descriptive statistics, measurement of central tendencies – mean, median, mode dispersion, standard deviation and coefficient of variation. Collection and presentation of data, probability distribution. Hypothetical tests of statistical significance. Analysis of variance, regression and correlation, experimental designs and clinical trails.
MLS422: VIROLOGY 2-0-3 (3 Credits)
Morphology and life cycle of viruses, nomenclature and classification of viruses – various methods. Reproduction and multiplication of viruses, resistance, pathology, collection of clinical specimens for viral culture. Culture methods for isolation of viruses, purification, immunity, laboratory diagnosis of viral infection. Haemaglutination test, CFT, Neutralization test, systematic study of viral diseases. Interferon, immunotherapy and chemotherapy in viral infection, inclusion bodies and cytopathic effects. Viral and host interactions and identifications, Viral vaccines and immunoprophylaxis.
MLS423: INTRODUCTION TO HISTOPATHOLOGY TECHNIQUES AND MUSEUM 2-0-3 (3 credits)
Principle of photochemical methods. DNA – demonstration by Feulgen techniques. Silver impregnation methods. Genes and genetic code. Tissue culture techniques; chromosome analysis. Autoradiography – Definition and principle. Organization of a medical Museum. Method of colour maintenance. Fixation and storage of museum specimens. Special museum techniques e.g Dawson’s Method. Principle of photography- Macro and Microphotography. Preparation of stained sections for microphotography. Preparation of specimens for macro photography. Cytological normal cells. Histology of tissues. Atypical and malignant cells. Collection of cytological smears and processing and screening. Principles of general pathology. Systemic pathology. Gastrointestinal tract. Urogental, coetaneous. Principle of electron microscopy. Practical based on the topics.
MLS424: BIOMEDICAL ENGINEERING 2-0-0 (2 Credits)
Workshop practice. Principles of use, maintenance and repair of common apparatus and laboratory equipment. Principle of applied and general electronics. Circuit diagrams computer programming. Improvisation. Glass blowing and construction of simple laboratory equipment. Design techniques, improvement on existing equipment, review and modifications of laboratory methods.
MLS425: BIOTECHNOLOGY AND BIOINFORMATICS 2-0-3 (2 Credits)
General preparation and storage of reagents for diagnostic use. Preparation and purification of antibody and antigen for diagnostic tools. Monoclonal and polyclonal antibodies. Concepts of vaccination. Preparation, purification and storage of vaccine. Introduction to Mathematical and Computation Genomics. Its application to medicine in general and laboratory diagnosis specifically.
MLS426: COUNSELING SKILLS 2-0-0 (3 Credits)
Definition of counseling, care and support, types of counseling pre-test, post-test prevention primary or secondary, crisis management, problem solving, decision making couple spiritual and pastoral; who needs counseling Prospect/benefits of counseling constraints in counseling, rewarding listening skills, prevention and managing conflicts. Genetic counseling including sickle cell trait in marriage, Blood donation campaign HIV infection etc. Case studies.
MLS 427: IMMUNOLOGY/IMMUNOCHEMISTRY 2-0-3 (2 credits)
Immunoglobulin-Structure and infection. Gene Organization and assembly. Mediators of cellular Immunity. Phagocytic cell- Chemotaxis and effectors function of Macrophage and Granulocytes. The complement system. Laboratory methods of detection of antigens and antibodies. Autoimmunity, Tissue and Graft reactions Immunotolerance, self and nonself, Histocompatibility, Transplantation, Tumor Immunology, Hypersensitivity and allergy.
500 LEVEL COURSES:
GENERAL COURSES FOR ALL THE STUDENTS
FIRST SEMESTER
MLS510: LABORATORY POSTING V (SIWES) 0-1-6 (3 credits)
Each student undergoes on the bench training in the different analytical techniques used in the area of specialization. The students are to participate in the routine operation of the laboratory. Log books are kept by each student under the supervision of a qualified medical laboratory scientists.
MLS511: SEMINAR 0-2-0 (2 credits)
Students are to carry out intensive literature research and present seminar on selected approved topics to the Departmental colloquium. Each presentation will be for about 15 to 20 minutes followed by general discussion. The presentation will be scored by the group of internal assessors appointed by the department.
MLS512: RESEARCH METHODOLOGY 3-0-0 (3 Credits)
Introduction to research methodology. Collection of literature review articles. Problem definition. Sampling techniques. Experimental designs of medical and data public health studies. Questionnaire design and data collection analysis. Interpretation and utilization of research findings. The role of research in health and social welfare. The need for institutional and governmental ethnical clearance for some research Aims, characteristics and application of biostatistics. Measures of central tendencies and variation. Collection and presentation of data. Probability sampling. Test of statistical. Significance. Experimental designs and clinical trials. Other applications of biostatistics to clinical and preventive medicine projects. Research proposals and sourcing of funding for research projects. Arts of scholarly publications, and instructional design.
MLS513: CYTOGENETICS 2-0-0 (2 Credits)
Theory and practice of clinical cytogenetics. Chromosome analysis, structure, organization and staining techniques. Chromosomes in man Normal karyotype and chromosome abnormalities. Mosaicism, trisomy, monosomy, translocation Klinefelters and Turner’s syndromes, sex chromatins. Inactivation of X –chromosome and sex determination. Genetic diseases. Clones, mapping of autosomes, DNA synthesis, gene in kindred segregation. X-linked inheritance. Chimeras. Genes in families and population. Selection, pedigree analysis, mutation and mutagens, Hardy Weinberg equation, genetic drift, inbreed. Slide reporting. Philadephia and Christ church chromosomes.
SECOND SEMESTER
MLS520: LABORATORY POSTING VI (SIWES) 0-1-6 (3 Credits)
Each student undergoes on the bench training in the different analytical techniques used in the area of specialization. The students are to participate in the routine operation of the laboratory. Log books are kept by each student under the supervision of a qualified medical laboratory scientists.
MLS521: GENETICS AND MOLECULAR BIOLOGY 3-0-0 (2 Credits)
Genomic Gene purification and amplification, polymerase chain reaction technique. Construction of genetic maps. Biotechnology – recombinant DNA, Hybriodoma.
MLS522: PROJECT 0-0-8 (6 Credits)
A supervised research project on an approved topic to be undertaken by each student for the partial fulfillment of the BMLS degree requirement. Assessment of the project will be by both oral defense and grading of the project content.
CLINICAL CHEMISTRY SPECIALTY
MLS531: CARBOHYDRATE, PROTEIN AND LIPID METABOLISM 2-0-3
(3 Credits)
Carbohydrate metabolism and disorder. Pathophysiology of diabetes mellitus. Diabetic ketoacidosis, Hyperosmolar non ketotic coma, lactic acidosis, Glycogen storage diseases.Insulinoma. Diagnostic criteria and Laboratory investigation. Fasting Plasma glucose, random plasma glucose, glucose tolerant test, pancreatic hormones and glycosylated hemoglobin. Lipid lipoproteins and apoproteins structure, composition and function, Intravascular metabolism and catabolism of lipoproteins. Disorders of lipid and lipoproteins. Lipid storage diseases. Cardiovascular function test. Recent advance in diagnosis of lipids disorders. Plasma proteins in health and diseases. Definition, cause and investigation of Para protein; Bence Jones proteinuria) and significance. Fractionalization of proteins. Protein electrophoresis in health and diseases. Protein degradation. Metabolic disorder and regulation of amino acid metabolism.
MLS532: RENAL, LIVER & NEUROCHEMISTRY 2-0-3 (3 Credits)
Physiology of kidney, renal clearance and glomerular filtration rate. Renal plasma flow, maximal tubular excretory and reabsorptive capacity. Urea, creatinine and insulin clearance. Concentration and dilution tests. Renal failure, azotaemia, anurea, sodium loss in renal diseases. Aminoaciduria. Kidney diseases and kidney function test. Urinalysis in health and diseases. Features of hypernatraemia and hyponatraemia. Investigation of water and electrolyte imbalance. Homoeostasis in clinical chemistry. Acid-base balance.
The liver anatomy and physiology-an overview. Biosynthesis of bilirubin, excretion of bile pigments. Jaundice anatomical and physiological classification. Pigment excretion in jaundice. Liver diseases and liver functions test to include congo red test for amyloisis and faecal fat estimation. Biochemistry of Neoplastic disorders. Diseases of the nervous system. Basic neurochemistry, CSF –normal composition and changes in diseases. Diseases of muscles.
MLS533: CLINICAL ENZYMOLOGY 2-0-3 (3 Credits)
Mechanics of Enzyme action and kinetics, Activation repression phenomenon. Enzyme induction, inhibition, purification and specificity. Clinical Enzymology; Coenzymes and Isoenzymes in medicine, diagnosis importance of isoenzymes in biotechnology.
MLS534: NUTRITION AND CLINICAL VITAMINOLOGY 2-0-0 (2 Credits)
Vitamins History and biochemical functions. Chemistry and metabolism of water and fats soluble vitamins. Their deficiency states and physiological significance. Relationship with hormones. Vitamin in health and diseases. Methods of analysis. Trace elements-Bioavailability , biochemical function, metabolism, and interaction. Hormonal control and methods of analysis. Specific elements in health and diseases. Bone diseases and investigation of bone disorders. Types, causes ETC. Causes and Investigation of nutritional disorders.
MLS535: DRUG MONITORING, TOXICOLOGY AND INBORN ERROR OF METABOLISM 2-0-3 (3 Credits)
Introduction to assimilation, distribution, elimination and excretion of drugs. Practical and theoretical aspect of poisoning. Investigation of suspected cases of poisoning. Estimation of blood alcohol, Salicylate sulphonamide, cyanide, oxygen, CO2, ammonia and Detection of barbiturate, cocaine heroin, opium, phenothiazine, methaqualone etc in blood, urine, sweat, aspirates, etc. Porphyrin, causes, symptoms and laboratory investigation of porphyrinaemia, porphyria and porphyrinuria. Haemoglobin, synthesis, Chemistry of Haemoglobinopathies, Sulp Hb, CoHb, Met Hb. Definition, causes, consequences and investigation of some inborn errors of metabolism; Phenylketonuria, galactosemia fructose intolerance, Albinism, aminoaciduria.
MLS536: CLINICAL AND REPRODUCTIVE ENDOCRINOLOGY 2-0-3 (3 Credits)
Endocrine glands-organization. Cellular communication by endocrine glands. Endocrine receptor binding control of endocrine action. Endocrine glands functions; the hypothalamus, the pituitary, the parathyroid, adrenal cortex, adrenal medulla. The gonads and reproductive endocrinology. Foeto-placental function. Endocrine control of metabolism and endocrine diseases/disorder; water balance, insulin action thyroid hormone and reproduction. Investigation of male and female infertility.
MLS537: TECHNIQUES IN CLINICAL CHEMISTRY 2-0-3 (3 Credits)
Analytical techniques, standardization and quality control. Validation of assay. Birth of a new method, devising new techniques. Biological trial and tests for acceptability. Solid/dry phase chemistry. Dipstick technology, thin film technology. Immobilized enzymes. Functional test in clinical chemistry. Liver function test. Renal function test. Gastro intestinal function test etc. Analytical techniques employed in qualitative and quantitative. Determination of (1) Enzymes-phosphates. Transaminases, Dehydrogenases, kinases(2) Hormones (3) protein-Total proteins, Albumin and globulin specific protein (4) Lipids-cholesterol, triglycerides glycerol, fatty acids and lipoproteins. (5) Trace elements-Fe, Cu, Zn, Mg, selenium (6) Non-protein nitrogen-Urea, creatinine, uric acid, amino acids and ammonia, urinalysis, determination of urine specific gravity, osmolarity, qualitative tests for protein, glucose and reducing substances. Ketone bodies, bilirubin, urobilinogen and blood. Haemoglobin and haemoglobin derivative in urine. Spectroscopy of Haemoglobin and its derivative in blood and urine. Astrup techniques. Chromatography, spectroscopy, spectrophotometry and photometry, AAS, Flame Photometer, (AES), Radioimmunoassay, ELISA and EIA.
HAEMATOLOGY AND BLOOD TRANSFUSION SCIENCE SPECIALITY
MLS541: HAEMOPOIESIS, HAEMOGLOBIN, HAEMOGLOBINOPATHIES &
MYELOPROLIFERATIONS 2-0-3 (3 Credits)
Erythropoiesis and blood. Blood cell counts in health and diseases. Blood indices. Anaemias, disorders of Iron metabolism, vitamin B12 and Folate deficiencies, Haemochromatosis and related storage disorders. The spleen and splenomegaly syndromes. Drugs, chemical and the blood Haemoglobinopathy, Haemoglobin genotype and phenotype.
Blood in infancy, childhood and pregnancy, Hereditary and blood disorders. Blood in microbial infections. Identification of blood parasites Immunohaematological disorders, autoimmune diseases, thrombocytopenia, leucopenia, Leukemia systemic and disseminated lupus erythematosus, rheumatoid arthritis myelomatosis and order paraproteinaemisa. Preparation and cytology of blood and bone marrow films in health and disease.
MLS542: BLOOD GROUP SYSTEMS AND COMPATIBILITY TESTS 2-0-3
(3 Credits)
ABO and other blood groups- MNS, KELL, Kidd, Duffy, Lewis, p-1 etc. Antenatal Serology; Hemolytic diseases of the newborn. Type, etiology, antenatal and post natal management. Blood group serology in paternity dispute. Haemolysin titration. Absorption and elution techniques. Indication and complication of blood transfusion. Red cell survival tests— radioisotope and differential agglutination methods. Screening of blood donor for infective agents – HIV, HBV, malaria, filarial, trypanosomes, syphilis, etc. anonymous result in blood grouping. False positive and false negative result in compatibility testing. Preparation and standardization of AHG.
MLS543: SEROLOGY AND BLOOD TRANSFUSION SCIENCE 2-0-3 (3 Credits)
Leucocytes and platelet antigen and antibody. Auto-immunization IgM, IgG, IgA antibodies. National Blood Transfusion Service. Preparation of commercial quantities of polyclonal antisera. Principles, uses and techniques of producing monoclonal and polyclonal antibodies. Types of blood substitutes and preservations. Preparations of blood products. WHO standards in BGS. Red cells membrane structure in relation to blood antigen locations.
MLS544: ADVANCED HAEMATOLOGICAL TECHNIQUES 2-0-3 (3 Credits)
Principles and techniques of Isoelectric focusing. Protein separation of column chromatography. Finger printing, principles and techniques. Purification of proteins and enzymes. Ultracentrifugation and molecular weight determination. Culture of blood cells and parasite. Leukocyte typing platelet aggregation- principles and techniques. Radioisotopes in Heamatology; Isotope labeling techniques, measurement of radioactivity Fluorescent antibody techniques. Radioimmunoassay, ELIZA, western blotting immunoelectrophoresis, competitive protein binding. Automation in Haematology, Electrophoresis- starch agar gel and polyacrilamide gel and polyacrilamide gel. Principle of polymerase chain reaction. Cytochemical procedurces. Lymphocyte Transformation Tests. Paul—Bunnel. test.
MLS545: ADVANCED BLOOD GROUP SEROLOGY TECHNIQUES 2-0-3
(3 Credits)
Techniques for emergency compatibility testing – low ionic sucrose solution, spin coomb’s albumin special compatibility techniques Exchange and extracorporeal blood transfusion. Preparation of enzymes used in BGS. Forensic application of BGS, Two stage Coomb’s technique Automation in BGS- Group and cross matchings Techniques, autoanalysers for antibodies and antigen detection and identification, etc.
MLS546: COAGULATION AND FIBRINOLYSIS STUDIES 2-0-3 (3 Credits)
Platelet functions, normal and abnormal haemostasis, measurement of bleeding time. Vascular integrity. Coagulation factors, Assessment of coagulation time. One stage prothrombin time, “Thrombotest” Thromboplastin generation. Haemophilia state, assay of anti-haemophilic factor (VIII), recalcification time. Fibrinolytic activities, rapid demonstration of fibrinogen deficiency. Simple assessment of fibrinolysis. General Principles underlying clotting factor assay and measurement of fibrinolytic activity. Platelet substitute solutions. Fibrin plates. Control of anticoagulant therapy.
HISTOPATHOLOGY SPECIALTY
MLS551: FUNDAMENTAL HISTOPATHOLOGY 2-0-3 (3 Credits)
Fixation: Purpose and effect of fixative composition and uses of fixatives and their respective action on tissue components. Microscopic appearance of tissues after various methods of fixation. Function and scope of secondary fixation , post fixation and post mordantings. Knowledge of fixation of tissues for histochemical methods to include freeze drying and freeze drying substitutes. Decalcification – processing techniques – paraffin wax, embedding media for mechanical and manual processing. Microtomy – Microtomes (manipulation and uses of rocking, rotary, sledge, freezing, cryostat and ultra microtomes), knives – selection and maintenance for various microtomes, manual and mechanical sharpening. Section cutting (techniques used with different embedding media, attachment of sections to slides-frozen section techniques method for rapid diagnosis.
MLS552: SYSTEMIC HISTOPATHOLOGY 2-0-3 (3 Credits)
This course exposes the students more into general pathology, control of results and management of Histopathology laboratory. More facts of Electron microscopy and Autoradiography are highlighted. Principles of general pathology applied to individual organs. Systemic Pathology. Hypertensive heart disease, heart failure and cardiomyopathies. Respiratory – Tuberculosis, pneumonia, Nephropathy associated with infestations and infections. CNS, special senses. Malignant lymphomas (non-Hodgkins and Hodgkins lymphoma, Burkitts). Idiopathic-tropical splenomegaly syndrome. Liver –cirrhosis liver cells carcinoma. Hepatitis. Female reproductive organs –pelvic inflammatory diseases. Cancer-cervical, trophoblast, ovarian. Skin leprosy, kaposis sarcoma. Electron microscopy- preparation of materials for electron microscopy. Toxicity of some reagents used in Electron microscopy. Techniques involved in autoradiography, Laboratory Management. Quality control and automation in histopathology laboratory. Slide Reporting.
MLS553: HISTOCHEMISTRY AND HISIOLOGICAL TECHNIQUES 2-0-3
(3 Credits)
Enzyme histochemistry and its diagnostic application. The theory of stains and application, metallic impregnation and various histochemical methods. The dye theory. Properties of natural and synthetic dyes. Composition, preparation and storage of staining reagents. Testing of reagents. Common nuclear stain and counter stain for general tissue structures. Staining methods to demonstrate elastic, connective tissues and fibers. Toxicity of some reagents used as it applies to auto-radiography , electron microscopy and ultra microtomy. Suitable fixatives for use, processing techniques, impregnation/embedding and slide preparation /interpretation.
MLS554: MEDICAL CYTOLOGY 2-0-3 (2 Credits)
Study of epithelial cells. Introduction/definition of medical exfoliative cytology. Definitions and principle of exfoliative cytological methods. Gynaecological and non gynaecological cytology. Cytology of normal and malignant cells. Diagnostics criteria for all malignancy. Kinds of tumours. Methods of collection of samples for gynaecological non gynaecological. Types of fixatives used. Staining techniques applied. Hormonal evaluation/assessment . Identification of virus, parasites. Micro-organisms and fungi in smears. Slide identification/interpretations. Principle of liquid basal cytology. Usefulness and advantages, disadvantages and diagnostic application.
MLS555: EMBALMENT SCIENCE AND MUSEUM TECHNIQUES 2-0-3
(2 Credits)
History and science of embalmment. Formalin based embalmment techniques. Other methods of preservation of dead, cryopreservation (history, procedure and applications) and mummification (history, procedure and applications). Different embalment techniques and problems. Museum mounting of whole organs, techniques, importance and application. Factors affecting embalming fluids. Setting up a mortuary/medical museum. Forensic pathology as it applies to post mortem examination, recording of pathological changes of organs and collection of clinical data during autopsy especially as it relates to drowning poisoning, strangulation e.t.c. Practical based on the above topics are adviced. Dogs/goats can be used for practical exercise.
MLS556: IMMUNOCHEMISTRY 2-0-3 (2 Credits)
Immunohistochemistry/immunocytochemistry, basic principles, staining procedures and techniques. Peroxidase and anti peroxidase major histocompatibility. Immuotyping of tumors, proteins and other diseases. Antibody and antigen preparation from cells and tissues. Human leucocytes antigen. Reading and interpretation of immunohistochemical/ immunocytochemical stained slides. Preparation and production of immunohistochemical/immunocytological stains.
MLS557: STAINS AND STAINING TECHNIQUES 2-0-3 (3 Credits)
Rapid H&E Frozen section, grams techniques. Maccivello techniques, phloxine tetrazine, ziehl nelson, Perl’s Prussian blue, schmorl’s reaction, Masson Fontana, Feulgen Reaction, Giemsa, H&E, Gordon and Sweets, Haem Van Gieson, P.A.S., Jone’s Mathenamine Sliver, Congo Red, Verhoeff’s MSB,PAS/Orange G.,Aldehyde fuchsin, Heidenhains iron haem, P.T.A.H., Alcian blue/PAS, Best’s Kossa, Oil Red O., Nile bule method. Bieschosky’s method, Marsland, Glee’s method, papannicolaou, Barr body count, Hormonal Evaluation Gynae.
MEDICAL MICROBIOLOGY SPECIALITY
MLS561: SYSTEMATIC BACTERIOLOGY 2-0-3 (3 Credits)
History of pathogenic microbiology. Normal body flora, pathogens sources of infection, laboratory diagnosis and identification of bacteria. The pyogenic cocci, (Staphi, Strep, Pneumococci and Neisseriae). The enterobacteriaeceae, coliforms, gastroenteritis, samonellosis, Shigallosis, choleras, Vibrios, Pseudomonae, Bacteriodes etc. The Haemophlic bacillus (haemo philus, Brucellae, Yersinia, Bordetella etc. Anaerobic Spore formers, Aerobic spore formers, (Bacillus, Clostridia, Spirochetes, Mycobacterium), Rickettsiae, Chalamydiae Mycoplasma, L-forms, Listeria, Erysipelothrix, Bartonella etc. General pathology, epidemiology, features, diagnosis, control and therapy anaerobiosis
MLS562: ADVANCED ENTOMOLOGY 2-0-3 (3 Credits)
Structure and classification of Arthropods of medical importance. Dipterial:- Families – Culicidea, Psychodidae, Sunuliidae, Ceratopogonidae, Tabanidae, Muscidae, Calliophoridae, oestridae, Hemiptera: Families – Cimicidae, Reduviidae Anoplura: Family – Pediculidae Siphonaptera: Families – Pubicidae, Ceratophillidae, Leptosylliae, tungidae Acerina:- Families- Ixodidae, Argasudae, Trombiculidac, Sarcoptidae, Demodicidae, Dermanyssidae, Poroceohalidae, Liunguatulidae
Special Topics
The epidemiology and geographical distribution of human diseases. Larval migrants. Group Spirochaetaccea Immune reactions (serology).
MLS563: PUBLIC HEALTH MICROBIOLOGY 2-0-2 (3 credits)
General principles of microbial disease transmission – waterborne, airborne, food borne, arthropod-borne and contagious disease. Principles and techniques for water treatment, waste-water disposal. Preventive measures in the control of bacterial, parasitic and viral infections. Vaccines and immunisation. Immunisation programme and schedule (EPI).
MLS564: MEDICAL MYCOLOGY 2-0-3 (3 credits)
General characteristics of fungi’s diseases, types of mycoses and properties; opportunistic fungi, Diagnosis and chemotherapy, Systemic mycosies (Cryptococcosis-Blastomycoses, Histoplasmosis, Coccidiodomycoses). Opportunistic mycoses (candidaesis, Phycomycoses; sporotrichoses, Chromoblastomycosis, etc.) Cutaneous mycoses- Dermatophytoses. Superficial mycoses. General properties, pathogenesis, diagnosis, epidemiology, control and recognition of fungi.
MLS565: MEDICAL VIROLOGY 2-2-0 (3 credits)
The dermatropic and viscerotropic viruses. Smallpox, cowpox, and vaccination; measles, rubella, chickenpox and shingles, Herpes Viruses,Yellow fever, lassa fever, Hep A, B and C, influenza, arbo viruses. The neurotropic viruses (rabies, poliomyelitis, encephalitis, Lymphocytic Choriomeningitis viruses, mumps, viral transformation and types of tumors and viruses. Oncogen theory etc. Viral gastroenteritis, Miscellaneous, viruses, vaccines, production and immunization.
MLS566: PHARMACEUTICAL MICROBIOLOGY AND MICROBIAL GENETICS
2-0-3 (3 Credits)
Principle of Antibiotics and chemotherapy. Mode of bacterial resistance to antibiotics. Sensitivity testing. Preparation of antibiogram dics. Minimum inhibitory concentration of antibiotics. History of antibiotics, mode of action, classification, antibiotics assay, use of animal model in the study of microbial infections. Evolution and inheritance mutation. Bacterial DNA in hereditary and mutation. Molecular basis of mutation, isolation of mutants. bacteriophages, plasmids, episomes, transposons and bacterial DNA transfers. Recombinant DNA technology and its applications.
MLS567: LABORATORY TECHNIQUES IN MICROBIOLOGY 2-0-3 (3 Credits)
Culture media (Different types, compounding from basic constituent and preparation of media). Examination, cultivation and identification of bacteria from different samples, pleural, csf, urine, sputum, ascitic fluid. Blood culture, High vaginal swab, wound swabs, ear, eye, nasal and other swabs. Stool bacteriology. Sputum bacteriology. Urine bacteriology. Systemic fungal culture and identification. Semen analysis. Special -serological tests. ASO, Widal, VDRL, Rheumatoid factor. Complement fixation, neutralization, haemagglutination tests for identification of micro-organisms. General identification of microorganisms by animal inoculation. Biochemical test for the identification of bacteria and fungi.