Background
The Department of Haematology and Blood Transfusion was established in 1979, from the
hitherto Department of Pathology which comprised the four subunits: Haematology, Medical
Microbiology, Chemical Pathology and Morbid Anatomy. Since its establishment, the
department has been headed by the following:
Name Duration in Office
Philosophy and Objectives
Our objectives are to:
Provide high quality and simplified medical education (in haematology) to undergraduate
medical students.
Provide appropriate and adequate practical exposure in haematology to undergraduate
medical students.
Train medical undergraduates on the correct interpretation and clinical application of
haematology investigation results.
Our Vision
Our vision is to be a leader in terms of academic excellence in haematology researches
and in the training of medical undergraduates on basic and professional knowledge and
competence in the provision of care for patients with blood and blood related disorders.
Our Mission
Our mission is to produce medical graduates with sound knowledge and competence in
haematology laboratory diagnostics, clinical care of patients with blood and blood related
disorders.
Faculty
Name Status Qualifications URL link to Google Scholar
account
1 Halim NKD Professor MB.BCH, FMCPath,
Cert. Haematology
(London),
Cert. Virology
(Baltimore).
2 Enosolease ME Professor MB.BS, FMCPath https://scholar.google.com/citati
ons?hl=en&user=HMNrIDUAA
AAJ
3 Awodu OA Professor MB.BCH, FMCPath. https://scholar.google.com/citati
ons?hl=en&user=mZbhiZEAA
AAJ
4 Omoti CE Professor MB.BS, FMCPath https://scholar.google.com/citati
ons?hl=en&user=QQ-
kP1EAAAAJ
5 Bazuaye GN Professor MB.BS, FMCPath,
Cert. Stem Cell
Transplant (Basel).
6 Nwogoh B Senior
Lecturer
MB.BS, FMCPath,
FWACP,
MSHS D&I Science
(Baltimore)
Technical Staffs
Name Status
Courses
Course code Description
HBT 302 Haematology I: Introduction
Blood cells and blood forming organs
Bone marrow structure and function
Haemopoiesis
Ineffective haemopoiesis
Haemoglobin: structure, function, synthesis and breakdown (haemolysis)
Physiological adaptation to anemia: role of 2,3 diphosphoglycerate (DPG).
Factors affecting oxygen dissociation curve.
Normal haematological values
Disparity in some blood counts in normal Nigerians and other black people in relation to
Caucasians (whites) (total WBC count, relative neutropenia and eosinophilia).
Definitions and classification of anaemia I.
Polycythemia: definition (including by RBC mass). Primary and secondary.
Abnormal RBC morphology in anaemia.
Systematic plan for the diagnosis of anaemia.
Indication for bone marrow aspiration and biopsy
Quality assurance in haematology
HBT 427 General Haematology II: Anaemia
Definition and classification of anaemia II
Microcytic anaemia: Iron deficiency, lead poisoning, thalassemia and anaemia of
chronic disorders.
Macrocytic anaemia:
Megaloblastic anaemia: Folic acid deficiency, vitamin B12 (including Pernicious
anaemia).
Anaemia due to bone marrow failure:
Myelophthisic anaemia, Aplastic anaemia.
Haemolytic anaemia: due to haemoglobin disorders
Sickle cell disorders, sickle cell trait and sickle cell disease; “balanced
polymorphism and Sickle cell gene”. Other haemoglobin variants that coexist
with sickle cell haemoglobin (Hb-C, Hb-D, Hb-E etc.
Other rare abnormal haemoglobin: Unstable haemoglobinopathies:
Methaemoglobinaemia and sulfhaemoglobinemia.
Haemolytic anaemia due to RBC enzyme deficiencies:
Glucose 6 phosphate dehydrogenase (G6PD) deficiency Protection of G6PD
deficiency against malaria. Lyonization theory.
Pyruvate kinase deficiency and other RBC enzyme deficiencies.
RBC membrane disorders
Spherocytosis and elliptocytosis
Acquired haemolytic anaemia
Immune haemolytic anaemia due to antibodies (idiopathic, Evans syndrome,
cold agglutinin antibodies, paroxysmal cold haemoglobinuria (PCH) and drug-
induced immune haemolytic anaemia. due to defects in RBC membrane
(including hereditary).
Microangiopathic haemolytic anaemia, prosthesis (cardiac) march
haemoglobinuria.
Haemolytic anaemia due to parasitic infections (malaria), bacterial pathogens
etc
HBT 517 Haematology: Blood Transfusion Medicine
Blood group systems: RBC antigens and antibodies
ABO blood group system
Rhesus blood group system
Blood donor selection and recruitment
Types of blood donor
Donor eligibility criteria
Blood bank serology
Blood grouping: cells and serum grouping, methods of blood grouping
Blood crossmatch
Antibody screening test: Direct and indirect Coomb’s (antiglobulin) test
Blood transfusion and transfusion reactions including transfusion transmissible
infections.
Blood and blood component therapy
Preparation and indications for use
Rationale blood use
Haemolytic disease of the newborn.
HBT 527 White blood cell disorders
Benign disorders of WBC:
Leukopenia
Leukocytosis and leukemoid reaction: neutrophilia, lymphocytosis, eosinophilia
(including tropical eosinophilia, hypereosinophilic syndrome
Diagnostic approach to lymphadenopathy
Infectious mononucleosis
Acquired immunodeficiency syndrome: HIV/AIDS
Structure and function of spleen
Disorders of the spleen: Hyposplenism, splenomegaly (including differentials of
massive splenomegaly), hypersplenism.
o Tropical splenomegaly syndrome
Molecular basis of cancers
Diagnostic methods in haematology: Morphology, immunophenotyping, cytogenetics,
fluorescent in-situ hybridization and molecular methods.
Haematological malignancies:
acute leukaemia (myeloid and lymphoid): definition, epidemiology, aetiology,
classification, clinical features, diagnosis, treatment and prognosis.
Chronic leukaemia: chronic lymphoid leukaemia, chronic myeloid leukaemia
Lymphoma:
o Non-Hodgkin’s lymphoma: aetiology, classification, epidemiology,
clinical features, diagnosis, staging, treatment and prognosis. Burkitt
lymphoma, diffuse large B cell lymphoma, mycosis fungoides
o Hodgkins lymphoma: aetiology, histologic types, epidemiology, clinical
features, diagnosis, staging, treatment and prognosis.
Myeloproliferative disorders: Polycythaemia rubra vera, essential
thrombocythaemia, idiopathic myelofibrosis.
Myelodysplastic syndrome (MDS)
Plasma cells dyscrasia including multiple myeloma.
Haemopoetic stem cell transplantation: introduction, types, conditioning,
complications and management of HSCT
Human leukocyte antigen (HLA).
HBT 528 Bleeding disorders and Thrombosis
Haemostasis
Bleeding disorders due to platelets: qualitative and quantitative disorders
Thrombocytopenia: differentials, clinical features, investigation and treatment
Congenital and acquired defects of platelet function
Test for platelet function
Bleeding due to coagulation disorders: genetic (haemophilia, von Willebrand disease)
and acquired disorders
Coagulation test: Prothrombin time, Activated Partial Thromboplastin Time, Thrombin
time
Defibrination syndrome: Disseminated intravascular coagulopathy (DIC)
Thrombotic disorders
Anticoagulant therapy: heparin, Coumarin, DOACS
Inhibitors and potentiators of anticoagulant
Monitoring of Warfarin therapy: International standardization index (ISI) and
international normalized ratio (INR).
HBT 518 Practical Haematology
Stains in haematology
Blood film preparation: principles and method of staining.
Identification of common haematologic disorders on peripheral blood films and bone
marrow films.
Full blood count – PCV, WBC, platelets.
Hb electrophoresis
Serological tests – blood grouping and crossmatch, Coombs test
Coagulation test – prothrombin time, APTT and correction test; ISI and INR calculation
and interpretation.
Nwogoh Benedict
Ag. Head of Department
